Trick or trap by One Carbon Therapeutics

Read a short story of One-carbon Therapeutics achievements so far in Nature Biopharma Dealmakers (https://www.nature.com/articles/d43747-023-00079-z). We are working hard to bring our novel inhibitor into the clinic.

Detailed mode of action of the MTHFD1/2 inhibitor TH9619 now published in Nature Metabolism

The One-carbon Therapeutics team is proud and excited to share our latest paper published inNature Metabolism describing the detailed mode of action of our potent MTHFD1/2 inhibitorTH9619 under development for difficult-to-treat cancers. It explains the inhibitor’s cancer specificityand emphasises the importance of utilising correct human-like conditions and cancer models in drugdevelopment. We show that cancer-specific […]